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New announcements from the Department of Defense:

Regenerative Medicine Focused Research Award (RMFRA) June 19, 2019

Pre-Application (Preproposal):
August 7, 2019

November 20, 2019

As part of the JPC-8/CRMRP, its regenerative medicine portfolio supports research aimed at providing solutions to repair, reconstruct, or regenerate tissue lost or damaged due to traumatic injury, particularly tissues of the extremities and craniomaxillofacial compartment. Regenerative medicine encompasses multiple approaches (engineered/synthetic, pharmacologic, biologic, and combinatorial) to the treatment of damaged tissues by using therapies that promote the self- regenerative capacity of the body. To address this effort, the JPC-8/CRMRP is offering the Regenerative Medicine Focused Research Award (RMFRA) as its next iteration of the Armed Forces Institute of Regenerative Medicine, AFIRM III, in FY19 to continue its effort to support the development of regenerative medicine solutions.

To meet the intent of the award mechanism, all projects submitted under the FY19 JPC-8/ CRMRP RMFRA must address one or both of the following Focus Areas:

Peripheral nerve regeneration

Skeletal muscle regeneration

Efforts to regenerate peripheral nerve should focus on restoring maximal function. The goal for peripheral nerve regeneration should be accelerating functional recovery and/or reducing the need for autograft; efforts should not simply address metrics of nerve regrowth or conduits to cross nerve gaps. Similarly, efforts to regenerate skeletal muscle should extend beyond restoration of muscle bulk or structure and address restoration of maximal muscle function.

More information at the web site:


Restoring Warfighters with Neuromusculoskeletal Injuries Research Award (RESTORE)

Pre-Application (Preproposal):
September 3, 2019

December 16, 2019

The intent of the RESTORE mechanism is to provide support for research of exceptional scientific merit that proposes solutions for optimal management, treatment, and restoration following Service-related neuromusculoskeletal injury. Research will accelerate progress toward returning Warfighters to combat readiness following neuromusculoskeletal injury and will ultimately benefit all patients with such injuries.

To meet the intent of the award mechanism, applications must address one or more of the following Focus Areas:

- Solutions that accurately diagnose neuromusculoskeletal injuries in training and operational environments to optimize management and treatment decisions

- Solutions to accelerate recovery and restore Warfighter performance in training and operational environments

- Objective support tools to enable providers to assess function and performance throughout treatment and predict long-term outcomes

- Pain management strategies following acute and/or chronic neuromusculoskeletal injury that are fast-acting, long-lasting, and free of adverse side effects

- Optimization of Warfighter performance following limb trauma or loss. Examples include, but are not limited to, prosthetics and orthotic solutions (e.g., intuitive control and sensation, interface, interoperability, prescription, and training), as well as regenerative rehabilitation solutions addressing peripheral nerves, skeletal muscle, and/or bone. Technology development is allowed. Regenerative studies without a rehabilitative component are not responsive to this funding opportunity.

More information: